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the massive, but necessary funds required to support the important and carefully regulated research necessary to bring psychedelic therapies to market.
Mushrooms changed the world in the 20th century, some say. Others say, psychedelics are older than humankind. But instead of synthesizing molecules and providing it people in a clandestine manner, what if, proper systematic drug discovery and development was done to make psychedelics better?
Zeus gave Sisyphus the eternal punishment of forever rolling a boulder up a hill in the depths of Hades for his crimes of being a trickster and twice cheating death. “Then I witnessed the torture…
JoJo and I do a fortnightly (bi-weekly) newshour session on all things Neurotech spanning the academic and industry updates. This week we covered a few updates. Most important of all, it is the first women…
There’s no shortage of heartbreaking stories about men and women who have dedicated their lives to the service of their countries and endured unfathomable trauma. Add to this population the other sources of PTSD like car accidents, witnessing or experiencing violence – or even the threat of violence, sustained stress in traumatic situations (hello, COVID frontline workers – I’m looking at you), and you have an explosion in an untreated or treatment refractory population.
We are here to bring to you how the road to psychedelic renaissance was built. And if you think, it came from overwhelming people with data, just like how a typical scientist thinks, you would be amazed at the personalities who paved the way, as much as the ones that broke it for themselves and for the world.
We’ve spent some time already on the definition of psychedelics – and we’ll spend more time before this series is over. But, Skraps is a podcast whose roots are run deep in the sciences, we couldn’t ignore the topic of the basic pharmacology of psychedelics. This episode is a primer for citizen scientists and holds some intriguing information for the bonafide scientists among us.
Fear. Fear causes people to do amazing and improbable things. Fear of an enemy, fear of an unknown. They are powerful motivators and ones that Syndey Gottlieb embraced with every fibre of his professional being. The same man whose family would have been Nazi victims engaged in some of the most insidious “experiments” known to man – experiments based on the knowledge and tutelage of the same Nazi scientists who deployed the gasses that would have killed his own family.
In episode two of PsychedeRx, Peyote comes north to the good old US of A. And it’s not just for religious ceremonies anymore, either. Spanish conquistadors and European explorers, seeking to dominate the indigenous tribes, used Peyote to show force by banning its use and denying the tribes their spiritual practices. And we all know what happens when prohibitions are imposed – the use doesn’t stop, it just gets moved underground.
We explore the use, misuse, and history of psychedelics. In this episode, we will cover the most important question of what these substances are.
After this episode, we’re going to take a week or two sabbatical in order to wrap up our big project. In the meantime, have a listen to what we thought Skraps would be vs. what it has become – and maybe reach back and take a listen to one of our many, many amazing guests.
Daniel Powell and Navid Khodaparast are getting on peoples’ nerves. No, really. They’re disrupting everything you know, or think you know, about opioid use disorders and tackling the hardest part of helping people break free of the vice grip of addiction – acute withdrawal.
Howard is an MD and together with his friend and professional colleague, Mark Gelfand has created some of the landmark medical device companies in cardiology.
Arun and JoJo sat down with this year’s Conference Co-Chairs, Professor Thomas Stieglitz and Professor Silvestro Micera to find out what makes this particular conference so special
Join us for part 2 of the coverage on what it means to be and feels like a fellow in the Cleveland NeuroDesign Innovation Fellowship Program run collaboratively by the Case Western Reserve University and Cleveland Clinic.
Here we are joined by the inaugural cohort comprising: Efstathios Kondylis, Swarna Solanki, Patrick Smith and Nick Couturier with strong recognition for a Case Western Biomedical Engineering Alum, Michael Ackermann.
The next cohort applications are now open: https://www.clevelandneurodesign.org/application
Each of them have a unique story that led them to this point. They walk us through what drove them here, how the process was, their experiences, what they learned, gained and more importantly implement moving forward.
This one is surely one not to miss, as it exposes what it means to be in a program that teaches scientists and engineers how to innovate based on need., a principle well documented by the Stanford Biodesign.
It is not often that we get to cover and you get to hear the story of an innovation design program. This is part 1 of the chat on Cleveland Neurodesign Innovation Fellowship Program with Andy Cornwell of Case Western Reserve University and the Cleveland Clinic and the faculty at the program.
What is the difference between intelligence and wisdom and why should you care? Dr. Robert Sternberg introduces us to his theories of adaptive intelligence and his triangular theory of love. He provides insights as to how our society misdirects and prioritizes our focus on exactly the traits that lead us down untenable social and political paths. He also proves to us once and for all that it’s a bad idea to use an IQ test to get a first date.
There is a Vietnamese proverb that reads “Brothers and sisters are as close as hands and feet.” Theo and Stavros Zanos are perhaps one of the best personifications of this notion. They are independent, they accomplish vastly different things, yet they are perfectly paired and, at the end of the day, part of the same system.
We try to capture myriad voices on Skraps, but this one is legendary. Truly. If you don’t trust us, we have a few testimonials to prove it. Dr. Robert Hamlin is a DVM and Professor Emeritus at The Ohio State University (please don’t get Arun started on his Buckeyes) and he knows more about the heart (animals and humans) than any single person has a right to.
You can check out his prolific research publications here, but don’t miss out on the story behind the investigator as we take on the peer-review process, lab culture and contracts (get that heart rate up!), being an outsider to both of your own cultures, sleep and exercise, and InequalityInSTEM (which his wife aptly points out should be STEAM!) an effort driven by Dawn Taylor that TK whole-heartedly endorses.
Arun and JoJo speak with Juan-Pablo about each of the portfolio companies funded by APVC (Axon Therapies, Cala Health, CVRx, EXO, Neuspera, Presidio Medical, Saluda Medical, and SetPoint Medical) and then dive head-long into what it’s like to be a Puerto Rican American influencing the future of medicine, exploring what it took to get there, and what he’ll do now that he as arrived. Answer: He’s not just talking about it – “Hire someone, mentor someone, spotlight someone.” Check. Check. Check
Casterton worked her way through the bigs (Edwards Lifesciences, Boston Scientific, Stryker, and Verily) and picked up a thing or two along the way. She’s broken the land-speed record in medical device product development, built successful teams across continents, worked with Google, Verily and others to scale COVID testing sites in a pinch (entirely online, too), and is ready, willing, and able to share those lessons with you. She has also recruited some other impressive leaders to have a little fireside chat with you, too.
Join us as we talk to Professor Lynne Carpenter-Boggs about the new trends in final remains disposal – human composting (or more tactfully called Natural Organic Reduction). If you’ve tried to live a life of sustainability, why stop there? Why not let your final act of earthly love be 1.4 tons less carbon than cremation or burial?
Have you ever wondered or seen someone and thought they could be a psychopath or have psychopathic tendencies? What if you found out if you really had the all the attributes of being a psychopath?
Does it make you question everything you have experienced and have been through wondering what if you had flipped and why you hadn’t flipped yet?
Dr. Hubert Lim talks about how his love for biomedical engineering starts off with wanting to understand music preferences a.la Napster, then branching to auditory implants, invasive and non-invasive neuromodulation. We talk about his fantastic journey into figuring out a treatment for Tinnitus via his company, Neuromod Devices. They published a fantastic study by performing bi-modal stimulation of the brain using tongue stimulation and sound to treat Tinnitus.
As a wannabe vet and an artist who took up medical illustrations as a career, Alissa’s career has surely been an unusual one. She has mastered the art of pushing beauty and uncovering of sense of awe and fear into people’s minds with her illustrations of Zika, Ebola and now infamous – SARS-Cov-2.
In a world where “your”data is commoditized, how willing should one be to provide access to their deeper brain activities? Who should benefit?
It is an interesting journey from liposomal drug delivery to looking carbon nanotubes to graphene in Kostas’ case. While, in Carolina’s case how her journey through deep brain stimulation and diabetes franchise shaped her outlook and leadership skills/capabilities.
Kate recounts the story from her birth, to her varied upbringing, her interest in music and architecture, engineering to neuroscience. This is one amazing conversation.
Dr. Amanda Grannas leads us a fantastic journey of her experiences as an analytical chemist and how analytical chemistry is a topic that most people don’t think but still is such an important part of our life.
Challenging an age-old system in sport with data. Lessons and musings from a sports analyst, writer, and documentary filmmaker
Jarrod Kimber is an award winning documentary film maker. From humble beginnings in Melbourne to becoming a well known sports writer and documentary film maker, Jarrod has constantly used data to point to the fallacies, assumptions and substantiate where the game should go.
Your data won’t leave your phone/device – Artificial Intelligence hardware, Nanotechnology and Memristors
What if your device (be it a consumer device (like a phone or a driverless car) or a medical implant) was capable of doing all of this on the chip and enable real-time decision making.
Dr. Sanford Greenberg has overcome disability that affected him since he was a Junior at Columbia University. He has since overcome this limitation to chart an unprecedented success as an innovator, entrepreneur, in politics, administration and more recently, in philanthropy via his www.Endblindnessby2020.com campaign.
Pioneering the first transcatheter valve, Travails of an Innovator(s), Bringing together coronary stents and TAVR
The pioneer of the transcatheter valve shares his story on how innovation is a lonely sport.
Jason Osborne describe how he went from being a kid in South Central Pennsylvania to scuba-diving for fossils.
From engineered cardiac tissue to ceramic barbecue to employing artists in a science lab, cuttlefish to fashion, employing counter-insurgency methods learnt in battlefields in Afghanistan to turn science on its head